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Medical Microbiology 2008-09                                                           Syllabus Page 1

Medical Microbiology introduces basic principles and then applies clinical relevance in four segments of the
academic preparation for physicians: immunology, bacteriology, mycology, and virology. (Parasitology is covered
in the Pathology course.) This rigorous course includes many etiological agents responsible for global infectious
diseases. Because the territory covered by infections and the immune response expands each year, we focus on
pathogenic mechanisms in order to foster a student's ability to solve problems in their future clinical career.
Microbiology faculty present course material in 3 sections:

            I. Immunology (Fall-1)          II. Bacteriology (Fall-2)             III. Mycology/Virology (Winter)
                 a. 17 Lectures (22 hrs)                                               a. 4 Mycology lectures
                                                a. 18 Basic Lectures
                 b. 2 Dry laboratory                                                   b. Panel Mycologists
                    exercises                   b.     10 Clinical Integrations        c. 15 Virology topics
                 c. 6 Cases discussed           c.     2 Dry lab exercises                (21 hrs, including 7
                    with clinicians                                                       Clinical lectures)
                 d. 2 Review sessions           d. Interactive discussions             d. 4 Small group
                                                e. 1 Review session                       discussions

            The following teaching methods will be used to enable student mastery of material:
            1. Lectures cover the main learning objectives for each section, and are supplemented with:
                   (1) online quizzes
                   (2) small group discussion of clinical cases and correlations
                   (3) clinical diagnostic exercises
                   (4) newsgroup discussions
            2. Small Groups: During each section of the course, small group discussions focus on
                 issues tailored for the student's heightened understanding of pertinent topics. These
                 discussion groups encourage integration and review of basic concepts, but new
                 information will be delivered and deeper discernment will be accomplished in these
                 class meetings. Topics presented in small group discussions will be covered on
                 examinations; therefore attendance is required at all meetings (sign-in sheets shall
                 be monitored).
                  Small groups in each section are as follows:
                    Immunology                  Bacteriology                      Mycology/Virology
                       2 Dry Laboratory              clinical integrations           Mycotic panel discussion
                        exercises                     2 Dry labs                      4 discussion groups
                       6 clinical case               Multiple interactive             aimed at applying
                        studies                        sessions                         concepts to cases
            3. Quizzes: Weekly assessment of student digestion and correlation of all course materials
            will be made by web-based quizzing. This novel web-based system facilitates the student's
            ability to formalize concept integration throughout the course, and provides a graded method
            to practice under time constraint. Quizzes will be timed, and are designed to reflect
            examination questions. Quiz schedule is published (paper and online); adjustments will be
            provided as necessary. A small group of faculty will use IN-CLASS quizzes to substitute for
            Online Quizzes. Please stay tuned for Oct-Nov. dates where this will occur.

            4. Examinations: Each midterm section will culminate with a non-cumulative written,
            multiple-choice test where students demonstrate accomplishment of learning objectives.
            (Learning objectives comprise the first section of each lecture's handout.)
Medical Microbiology 2008-09                                                 Syllabus Page 2
Student performance in Medical Microbiology will be evaluated by a series of exams and
quizzes. Attendance at all course events is necessary for optimal performance, and material
presented in small group sessions will be graded and shall be included in quizzes and exams.
In light of pod-casting, students are reminded that confusion in lecture is most efficiently
cleared up immediately by questions in lecture rather than at later times.

Grades are not determined for individual exams. Final grades are determined according to
the ratios in the following table.

                               Number    % each     Total % of Final Grade
             Examinations         3        30%                 90%
             Quizzes              20       0.5%                10%

Following grade determination, teaching faculty from the Department of Microbiology meet
to set the Pass-Fail line at two standard deviations from the mean score.

Preparing prior to class will be the single most effective
mechanism to ensure success in Medical Microbiology Reading
assigned chapters in the textbook will logarithmically increase a
student's knowledge and will heighten both complete
understanding and efficient mastery of required material.

        Peter Parham, The Immune System, 2nd ed. (New York:
           Current Trends/Garland, 2005).

      Bacteriology / Mycology / Virology:
       Patrick R. Murray, Ken S. Rosenthal, Michael A. Pfaller.
           Medical Microbiology, 5th ed. (Philadelphia:
           Elsevier/Mosby, 2005).

Levinson, W. Review of Medical Microbiology and Immunology,         9th ed. LANGE REVIEW
   SERIES (NY: McGraw-Hill, 2006).

Harvey, R.A., P.C.Champe, and B.D. Fisher. Microbiology, 2nd edition. LIPPINCOTT'S
   ILLUSTRATED REVIEWS (Philadelphia: Lippincott, Williams, & Wilkins, 2007).
Medical Microbiology 2008-09                                                   Syllabus Page 3

The Department of Microbiology endeavors to prepare candidates for the Doctor of Medicine
degree with the following professional objectives for their successful career. A student's
desire to practice these objectives in Medical Microbiology (and other undergraduate
medical education) will substantially enhance their knowledge, humility, and technical skill
for a successful and rewarding career.

1. Demonstrate respect for others
     a. Students are asked to attend all class meetings, particularly small group
     b. Students respond in dignified manner to faculty, staff, and student colleagues,
        exemplifying their maturity and empathy.
     c. Students agree to abide by appropriate biosafety practices when in BSL-2

2. Exhibit honesty and integrity
      a. Students abide by the Honor Code of the University of Virginia in all exams,
           quizzes, and graded assignments.
      b. Students discuss honestly any grading oversights or computer/technology errors
           with Course faculty as soon as discrepancies arise.

3. Practice concern through communication, respect, and understanding
      a. Students grasp opportunities to "rehearse" professional etiquette when dealing
          with faculty in situations of uncertainty and/or ignorance.
      b. Students appreciate the enormous benefits of faculty variation in education
          and/or background by seeking to understand diverse populations.
      c. Students encourage their classmates to heightened levels of understanding by
          promoting questions and through the support of shared personal experiences.

4. Perform assignments responsibly and with accountability
      a. Students complete open-book, online quizzes each week, according to the
          Section schedule.
      b. Students arrive promptly to classes as well as small groups activities.
      c. Students work effectively as a team member when assigned, realizing they gain
          more when fully engaged.
      d. Students seize the opportunity to learn from a diverse group of faculty instructors
          in small group settings, focused on basic relevance of clinical cases.

5. Seek excellence and scholarship
      a. Students strive to excel at all four areas of Medical Microbiology, including
         immunology, bacteriology, mycology, and virology.
      b. Students read to supplement the foundational scaffold of information presented
         in lecture.
      c. Students seek to develop treatment behaviors that will reduce the incidence of
         antimicrobial resistance in the world.
Medical Microbiology 2008-09                                                               Syllabus Page 4
Web: The course website ( ) contains
necessary information for successful completion of this course, including links to the following: lecture
notes, weekly quizzes, tutorials, practice exams, and laboratory/small group information. The website
will be updated throughout the course as new resources are necessary, and is considered to be the
most up-to-date reference for the course.

Review Core course material from First Year:
    Basic Biology
          o The Online Biology Book:
    Cell Biology:
          o The Virtual Cell
          o The Open Directory Project  Cell biology chapter
          o The Biology Project (U. Arizona)
          o The Dictionary of Cell and Molecular Biology
          o DNA from the beginning:
          o The Biology Project (U. Arizona)

Newsgroup: Answers to common conceptual questions are posted to the course newsgroup by fellow
      students and Microbiology faculty. In addition, students may submit questions by email
      ( ), and faculty will supply responses via the course newsgroup.
      The Newsgroup is also the first place to check when reviewing for exams, as lecture clarifications
      (and error corrections) will be made public on the Newsgroup first. Questions shall be addressed
      as "conversations" and a topic can have many entries to allow complete understanding of that
      topic. Students can reach the Newsgroup through our course website (address above).
      Remember, the most efficient way to have questions answered is to ask them in class! Delays
      often occur for email-submitted queries.

Email: Class meeting modifications, room changes, and schedule emergencies will be emailed
directly to students. To avoid extensive crowding of student email accounts, all general course
content questions and clarifications will be posted to the course Newsgroup (see above).

BUGS/POPS: These medical microbiology tutorials with case studies will be available for self-paced
learning throughout the semester. Students are encouraged to use BUGS, POPS, and the other
tutorials early in the course (particularly during the Immunology section) to facilitate familiarity with
infectious organisms prior to the large amount of information presented in Virology, Mycology, and

Microbes in Motion II: is an interactive electronic textbook with animations and quiz questions.
Intended primarily as a tutorial for the Bacteriology section of the course, there are also chapters on
Immunology and Virology that you may find helpful. This software is available on all Health System
Library computers.
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